Observational data suggest that testosterone levels in men may be a reversible risk factor for T2D and therefore inclusion of testosterone may enhance the performance of current type 2 diabetes risk tools.
There are currently at least seven risk models to identify those at risk of developing T2D. A recent study from South Australia, published in BMC Endocrine Disorders, aimed to determine whether low serum testosterone levels add clinically useful information to these T2D risk models.
The study showed that low serum testosterone levels predict an increased risk of developing T2D in men over 5 years independent of current T2D risk models used in clinical practice. However, more research is needed to confirm the results and assess whether testing men at risk of type 2 diabetes for low testosterone in addition to the current risk assessments would help with guiding interventions.